MS

Avidekel Cannabis extracts and cannabidiol are as efficient as Copaxone in suppressing EAE in SJL/J mice

Inflammopharmacology 2018

Ruth Gallily¹, Zhannah Yekhtin¹

¹The Lautenberg Center for General and Tumor Immunology, The Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem, Israel

Multiple sclerosis is an autoimmune disease that affects the central nervous system. The disease can be treated with immunosuppressive drugs that alleviate the symptoms and retard disease aggravation. An example of such a drug is Copaxone, an immunosuppressive medication that is used to alleviate the symptoms of multiple sclerosis. Recently, it has been shown that the cannabidiol component in the cannabis plant has a positive effect on the model of multiple sclerosis in animals, an acute, inflammatory disease that attacks the myelin sheath. The aim of this study, conducted in collaboration with the Hebrew University, was to compare the efficacy of purified CBD, extracts of CBD-rich Avidekel, and Copaxone.

STUDY POPULATION: Lab mice.

STUDY PRODUCT: Avidekel.

RESULTS:

• Avidekel may be useful in the treatment of multiple sclerosis symptoms.
• Avidekel strain extracts and cannabidiol are as efficient as COPAXONE® in immunosuppression in-vivo laboratory experiment examined the effect of multiple sclerosis symptoms in mice.
• Both CBD and Avidekel extracts efficiently inhibited the clinical symptoms appearing during all the study phases.

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