Clinical Studies

Over 14 years of clinical studies

PROSPECTIVE ANALYSIS OF THE SAFETY AND EFFECTIVENESS OF MEDICAL CANNABIS TREATMENT AMONG A LARGE POPULATION OF MEDICAL CANNABIS PATIENTS Frontiers in medicine 2022 Lihi Bar-Lev Schleider1,2, Raphael Mechoulam3, Inbal Sikorin4, Timna Naftali5, Victor Novack1,6 1Clinical Research Center, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Be’er-Sheva; 2Research Department, Tikun […]

Placebo-controlled study – Oral CBD-rich cannabis for Crohn’s disease Journal of Crohn’s and Colitis 2021 Timna Naftali1,2, Lihi Bar-Lev Schleider3, ShlomoAlmog2, David Meiri4, Fred M Konikoff1,2 1Institute of Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba affiliated with Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel; 2Sackler School of Medicine, Tel Aviv University, […]

Behavioral and Neurobiological Effects of Medical Cannabis Treatment in Mouse Model of Autism Spectrum Disorder Translational Pediatrics, 2021 Shani Poleg1, Emad Kourieh1, Angela Ruban2, Guy Shapira3, Noam Shomron3, Boaz Barak4,5,Daniel Offen1,3,4 1Sackler Faculty of Medicine, Human Molecular Genetics & Biochemistry, Felsenstein Medical Research Center, Tel-Aviv University, Tel Aviv, Israel; 2The George S. Wise Faculty of […]

Epidemiological Characteristics, Safety and Efficacy of Medical Cannabis in the Elderly European Journal of Internal Medicine, 2018 Ran Abuhasira1, Lihi Bar-Lev Schleider1,2, Raphael Mechoulam3, Victor Novack1 1Cannabis Clinical Research Institute, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be’er-Sheva, Israel; 2Research Department, Tikun Olam LTD, Israel; 3Institute for Drug Research, […]

Placebo-controlled study – Cannabis is associated with clinical but not endoscopic remission in ulcerative colitis PLOS ONE Timna Naftali1,2, Lihi Bar-Lev Schleider3, Fabiana Benjaminov1,2, Fred M.Konikoff1,2, Shelly Tartakover Matalon1,2,Yehuda Ringel1,2 1Institute of Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba; 2Sackler School of Medicine, Tel Aviv University, Tel Aviv; 3Soroka University Medical Centre and Faculty […]

Brief Report: Cannabidiol-Rich Cannabis in Children with Autism Spectrum Disorder and Severe Behavioral Problems—A Retrospective Feasibility Study J Autism Dev Disord, 2018 Adi Aran1 · Hanoch Cassuto2 · Asael Lubotzky1 · Nadia Wattad1 · Esther Hazan1 1 Neuropediatric Unit, Shaare Zedek Medical Center, 12 Bayit Street, 91031 Jerusalem, Israel; 2 Clallit HMO (Kupat Holim), Jerusalem, […]

Oral Cannabidiol Use in Children With Autism Spectrum Disorder to Treat Related Symptoms and Co-morbidities Frontiers in Pharmacology, 2019 Dana Barchel1, Orit Stolar2, Tal De-Haan1, Tomer Ziv-Baran3, Naama Saban4, Danny Or Fuchs1, Gideon Koren1,5 and Matitiahu Berkovitch1 1 Clinical Pharmacology and Toxicology Unit, Assaf Harofeh Medical Center, Tel Aviv, Israel; 2 Autistic Spectrum Disorder Clinic, […]

Real Life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy Scientific Reports, 2019 Lihi Bar-Lev Schleider 1,2, Raphael Mechoulam3, Naama Saban2, Gal Meiri4,5&  Victor Novack1 1Clinical Cannabis Research Institute, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Be’er-Sheva, Israel; 2Research Department, Tikun Olam LTD, Tel […]

Overcoming the Bell‐Shaped Dose‐Response of Cannabidiol by Using Cannabis Extract Enriched in CannabidiolPharmacology & Pharmacy, 2015 Ruth Gallily1, Zhannah Yekhtin1, Lumír Ondřej Hanuš2 1The Lautenberg Center for General and Tumor Immunology, The Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem, Israel; 2Department of Medicinal and Natural Products, Institute for Drug Research, The Hadassah Medical […]

Single Center Experience with Medical Cannabis in Gilles de la Tourette Syndrome Parkinsonism and Related Disorders, 2018 Avner Thaler1, Shira Arad1, Lihi Bar-Lev Schleider4, Judith Knaani1, Tali Taichman1, Nir Giladi1,2,3, Tanya Gurevich1,2,3 1Movement Disorders Unit, Neurological Institute, Tel-Aviv Medical Center, Israel; 2Sackler School of Medicine, Tel-Aviv University, Israel; 3Sagol School of Neuroscience, Tel-Aviv University, Israel; […]

Avidekel Cannabis extracts and cannabidiol are as efficient as Copaxone in suppressing EAE in SJL/J mice Inflammopharmacology 2018 Ruth Gallily1, Zhannah Yekhtin1 1The Lautenberg Center for General and Tumor Immunology, The Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem, Israel Multiple sclerosis is an autoimmune disease that affects the central nervous system. The disease […]

Treatment of Crohn’s Disease with Cannabis: An Observational Study IMAJ – The Israel Medical Association Journal, 2011 Timna Naftali 1, Lihi Bar Lev, Doron Yablecovitch, Elisabeth Half, Fred M Konikoff 1Institute of Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba affiliated with Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel. The marijuana plant […]

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