SAFETY AND EFFICACY OF MEDICAL CANNABIS IN FIBROMYALGIA
Journal of Clinical Medicine, 2019
1 Department of Rheumatology, Rabin Medical Center, Petach Tikva Israel; 2 Cannabis Clinical Research Institute, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Be’er-Sheva, Israel; 3 Research Department, Tikun Olam LTD; 4 Department of Rheumatology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Be’er-Sheva, Israel
367 Fibromyalgia patients participated in a prospective observational study with 6 months follow-up period. The aim of the study was to investigate the characteristics, safety, and effectiveness of medical cannabis therapy for fibromyalgia. Medical cannabis appears to be a safe and effective alternative for the treatment of fibromyalgia symptoms.
STUDY POPULATION: 367 fibromyalgia patients.
81.1% of patients reported overall treatment success – defined as experiencing at least moderate improvement in their condition without serious adverse effects.
Overall pain intensity reduced from a median of 9.0 at baseline to 5.0 after six months.
73.4% of patients reported improved sleep; 13.2% reported their sleep problems were fully relieved.
80.8% of patients reported improved depression‐related symptoms.
61.9% of patients reported their quality of life (QOL) to be “good or very good,” whereas only 2.7% of patients rated their QOL at this level prior to beginning treatment.
22.2% of patients stopped or reduced their dosage of opioids; 20.3% reduced their dosage of benzodiazepines.