Medical cannabis in Gilles de la Tourette’s syndrome

Cannabis and Cannabinoid Research, 2022

Barchel Dana1, Stolar Orit2, Ziv-Baran Tomer3, Itai Gueta4,Berkovitch Matitiahu1, Kohn Elkana1, and Bar-Lev Schleider Lihi5

1Clinical Pharmacology and Toxicology Unit, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel; 2Autistic Spectrum Disorder Clinic, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel, affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel; 3Department of Epidemiology and Preventive Medicine, School of Public Health, Tel-Aviv University, Tel-Aviv, Israel;4 Internal medicine A, Sheba Medical Center, Tel Hashomer, Israel, The institute of Clinical Pharmacology and Toxicology, Sheba Medical Center, Tel Hashomer, Israel, Sackler school of medicine, Tel Aviv University, Israel; 5Research Department, Tikun Olam – Cannbit Pharmaceuticals, Israel.

Tourette’s syndrome is a neurodevelopmental disorder characterized by vocal and motor tics and other comorbidities. Patients with Gilles de la Tourette syndrome experience reduced function and impaired quality of life. The current medical treatments for this syndrome can cause significant side effects and offer partial symptomatic relief. The aim of this study, conducted in collaboration with Shamir (Assaf Harofeh) Medical Center, was to describe the effect of medical cannabis treatment in patients with Tourette’s syndrome. The study found that medical cannabis may improve Tourette patients’ quality of life and comorbidities symptoms.

STUDY POPULATION:  70 Tourette patients (57 males, Median age 31 year)

STUDY PRODUCT:  Various Tikun Olam’s strains and products

Results:

57 patients (81.4%) remained in active treatment.

– Improvement in anxiety – Of 19 patients who reported an anxiety disorder, 89% reported an improvement, and 11% reported no change.

– Improved quality of life – Of the 43 patients answering this question, 69.8% reported an improvement, 25.6% reported no change, and 4.6% reported worsening.

– Change in the number of medications – 28 patients reported the use of conventional drugs for Tourette’s syndrome during the study period, using medical cannabis as a supplemental treatment. The average number of medications was 2 (range 0-7) before treatment and decreased to 0.5 (range 0-1) after six months of treatment.

– Improvement in obsessive-compulsive disorder – Of 9 patients who reported obsessive-compulsive disorder as a comorbidity, 67% reported an improvement, 22% reported no change, and 11% reported worsening of obsessive-compulsive disorder.

– Motor and vocal tics – No significant improvement was observed in motor and vocal tics.

– Side effects – The most frequent adverse events reported were dizziness (4 patients), increased appetite (3 patients), fatigue (3 patients) and dry mouth (3 patients).

FULL STUDY

Have you liked our facebook page?

Common Questions

Ordering Tikun Olam Products

Proudly leading the revolution for modern Cannabis treatment

Related Topics

Brief Report: Cannabidiol-Rich Cannabis in Children with Autism Spectrum Disorder and Severe Behavioral Problems—A Retrospective Feasibility Study J Autism Dev Disord, 2018 Adi Aran1 ·

Epidemiological Characteristics, Safety and Efficacy of Medical Cannabis in the Elderly European Journal of Internal Medicine, 2018 Ran Abuhasira1, Lihi Bar-Lev Schleider1,2, Raphael Mechoulam3, Victor

Medical Cannabis for Pediatric Moderate to Severe Complex Motor Disorders Journal of Child Neurology, 2018 Stephanie Libzon1, Lihi Bar-Lev Schleider2, Naama Saban2, Luda Levit2, Yulia

whatsapp

תודה על הגשת מועמדותך, במידה וקורות החיים ימצאו רלוונטיים ניצור קשר. בהצלחה!